Best Vitamin B12 Supplements of 2025

Feel like you’re constantly in a need of an energy boost? It might be time to assess your B12 intake. This key B-vitamin is essential for energy, immune, and cognitive health. Learn more and discover our top picks of 2025.

It’s normal to feel tired due to busy schedules, tough workouts, or a lack of sleep. However, if you’re feeling unusually sluggish or sleepy, low vitamin B12 might be the culprit. And you wouldn’t be the only one. Low B12 is thought to be fairly common, especially amongst older adults. [1]

Getting sufficient amounts of this vitamin is vital for so many important functions, from boosting your energy levels to supporting mood. Find out more about why vitamin B12 is absolutely essential for your health.

What is vitamin B12 and what does it do?

Vitamin B12, also known as cobalamin, is a water-soluble vitamin. This B vitamin is an essential nutrient that is involved in a number of important bodily functions, including:

Energy metabolism: This means that vitamin B12 is used to help convert food into energy.
Blood cell formation: Vitamin B12 is needed to make red blood cells. These carry oxygen to the body’s tissues, where it is used to produce energy. This key vitamin also plays a role in the immune system.
Nerve function: Vitamin B12 is also needed for the proper function of the nervous system. It helps to maintain nerve cells which are required to produce energy and communicate with each other.
DNA synthesis: Vitamin B12 is also involved in DNA synthesis, the process by which DNA is created and repaired.

Vitamin B12 is found in a variety of foods, including meat, fish, poultry, eggs, dairy products, and fortified cereals.

What are possible signs of low B12?

Not getting enough vitamin B12 in your diet can cause low B12 or even vitamin B12 deficiency (a lack of vitamin B12). Some signs include:

Note: These statements are not intended to diagnose, treat, cure, or prevent any disease or condition, nor are they intended to be substitutes for professional medical advice. Always consult your physician or other qualified healthcare provider for accurate advice, diagnosis, and treatment plan.

Who might benefit?

Vitamin B12 plays a significant role in maintaining our wellbeing and may benefit a wide range of people.

Despite its importance, some people may struggle to consume sufficient amounts of B12-rich foods each day and choose to turn to B12 supplements.

It is estimated that about 26% of the US population are low in vitamin B12. [1]

It’s important to bear in mind that we all have individual needs and supplements impact each of us differently. That being said, certain groups of people who may choose to use vitamin B12 supplements include:

People who mostly follow a plant-based diet: Vitamin B12 is naturally found in animal products, so people who are vegan, vegetarian, or mostly follow a plant-based diet may not get enough vitamin B12 from their diet.
People over the age of 50: The risk of low vitamin B12 increases with age.
People with certain conditions: Some health issues may interfere with the body’s ability to absorb vitamin B12.

Benefits of vitamin B12

Because vitamin B12 is vital for so many bodily functions, there are several benefits believed to result from getting enough of this must-have nutrient.*

Some potential benefits of vitamin B12 include:

Note: Individual results may vary. The benefits stated are based on personal experiences and subjective feedback and may vary from person to person.

Types of B12 Supplements

Vitamin B12 supplements come in a variety of different forms. The most common include:

Tablets: Easy to swallow and can be taken with or without food.
Capsules: Similar to tablets, but encased in a capsule which may make them easier to swallow for some people.
Gummies: Chewable supplements that may sometimes contain sugar or syrup amongst other additional ingredients.
Liquid: Available as drops or sprays.
Multivitamins: Quality multivitamins often contain vitamin B12 amongst other essential vitamins and minerals.

Top Way To Get Vitamin B12 Into Your Diet? Vitamin Stacking

Vitamin B12 supplements come in many shapes and forms, from capsules to liquids. One popular method some people use to support their B12 intake is through multivitamins.

There are many reasons to consider taking vitamin B12 in a multivitamin. In fact, a number of people choose to do so because it’s an easy way for them to “stack” their vitamins.

Never heard of vitamin stacking? Vitamin stacking is the practice of taking multiple vitamins and minerals together in order to help support absorption and, therefore, possible effectiveness.*

Vitamin B12 stacking is a specific type of vitamin stacking that involves taking vitamin B12 with other vitamins and minerals that are thought to work synergistically with it. Like:

Folate (Vitamin B9)
Magnesium
Copper

Iron
Selenium

Zinc
Vitamin D

Other reasons to consider taking vitamin B12 in a multivitamin include:

Convenience: Multivitamins offer a convenient way to get your daily dose of vitamin B12. They are easy to take and you only need to take one capsule per day.
Price: Multivitamins are relatively affordable, especially compared to some other forms of vitamin B12 supplements.
Other essential nutrients: Multivitamins often contain other essential nutrients, such as folate, magnesium, calcium, and vitamin D. This can be helpful if you are not getting enough of these through diet alone.*

What to look for in a vitamin B12 supplement

Methylcobalamin: The type of vitamin B12 in a multivitamin is important because some forms are thought to be more bioavailable than others. Methylcobalamin is thought to be more bioavailable than cyanocobalamin (bioavailability refers to how well a nutrient is absorbed by the body).*
Amount of vitamin B12: The amount of vitamin B12 varies from supplement to supplement. Consult with your doctor to help select the right amount for your individual needs.
Ease of use: You are more likely to be consistent with a supplement that best suits your lifestyle, needs, and personal preferences.
Other nutrients: If you are considering vitamin stacking, check the multivitamin label to determine which nutrients it contains.

What to try to avoid in a vitamin b12 supplement

Cyanocobalamin: This is a synthetic type of vitamin B12. Although it’s commonly used, it’s thought to be less bioavailable than methylcobalamin.*
Unclear labels: All high-quality supplements should clearly list exactly what’s included in the formula. Avoid products lacking transparency that don't clearly state the type of vitamin B12 contained in the B12 supplement.
Missing safety testing & certifications: Choose a supplement that has been independently third-party lab tested. These precautions will guarantee that the product is top quality and free from unwanted extras, such as contaminants, traces of heavy metals, or pesticides.
Choosing according to price: When it comes to your health, this is definitely not an area to test out suspiciously cheap products. Before you’re tempted to go for the cheapest option, keep in mind that there are plentiful options to choose from that are high value and still affordable.

1. Primal Multivitamin

by Primal Harvest[1]

GRADE

A+

PROS

Vitamin B12 as methylcobalamin
Includes 20 other vitamins and minerals including D3, C, and folate
Contains zinc, magnesium, and selenium
Includes citrus bioflavonoids plus the antioxidants lutein and lycopene
1 capsule a day
Made in the USA with globally sourced ingredients
90-day money-back guarantee
Third-party lab tested
Subscribe & Save program

CONS

BOTTOM LINE

Primal Multivitamin by Primal Harvest is a multivitamin that combines vitamin B12, in the form of methylcobalamin, with a wide spectrum of other body-ready vitamins and minerals. Its premium vitamin-mineral blend includes folate, vitamin D, magnesium, essential B vitamins, selenium, zinc, manganese, calcium and more. What makes this multivitamin unique is that it also features lutein, lycopene, and citrus bioflavonoid complex for added antioxidant properties. This multivitamin takes a comprehensive approach to supporting overall wellness and helping to fill nutritional gaps with its premium, easy-to-swallow once-daily capsules.*

Primal Harvest’s Primal Multivitamin is third-party lab tested and is made in the USA with globally sourced ingredients. The brand has a convenient Subscribe & Save program which means you can order this formula through their convenient and hassle-free subscription service. By signing up for a subscription you get 20% off all products plus free shipping. The brand also offers great deals if you purchase multiple bottles at once. To top it off, Primal Harvest offers a 90-day money-back guarantee on all of their products.

2. Vitamin B12 1,000 mcg

by Nutricost

GRADE

B+

PROS

CONS

BOTTOM LINE

Vitamin B12 by Nutricost is a once-daily vitamin B12 capsule that includes ,000 mcg of vitamin B12. Each bottle contains 240 capsules, making it an affordable option. However, some may want to note that the formula only contains vitamin B12, so those interested in combining vitamin B12 with other nutrients would need to supplement these capsules with other products.

Additionally, the brand has a slightly shorter returns policy than some of the others featured on this list.

3. Bio-Kult Boosted

by Bio-Kult

GRADE

B

PROS

CONS

BOTTOM LINE

Bio-Kult Boosted by Bio-Kult is a probiotic formula that includes vitamin B12. Although the formula contains a comprehensive range of probiotics, it does not contain other vitamins or minerals like folate. It comes in capsule form which should be taken once daily. Those with certain allergen concerns may want to note that the product contains milk and soy.

Other considerations include the 30-day returns policy and the fact that there is no information available on the website that confirms whether the product has been third-party tested.

4. Vitamin B12 1000 mcg

by Vispura

GRADE

C+

PROS

CONS

BOTTOM LINE

Vitamin B12 1,000 mcg by Vispura is a B12 tablet that also includes vitamin B6 and folic acid. This formula delivers vitamin B12 in the form of methylcobalamin but doesn’t include any minerals or other vitamins than the ones mentioned above. It comes in a bottle of 180 tablets and has a serving of one capsule per day.

Some may want to note that it can only be purchased in the US through a third-party retailer which means that the returns policy may differ according to the retailer’s policies.

5. Vitamin B12 500 Mcg

by Nature Made

GRADE

C

PROS

CONS

BOTTOM LINE

Nature Made Vitamin B12 is combined with calcium and delivered in a tablet that should be taken once per day. Although the formula also includes the mineral calcium, it doesn’t contain any other vitamins or minerals. One thing to note is that although the formula provides B12, it does so in the form of cyanocobalamin rather than methylcobalamin like many of the other products featured here.

Additionally, some may want to note the 30-day returns policy.

Our Choice

1. Primal Multivitamin

by Primal Harvest[1]

Vitamin B12 as methylcobalamin
With folate, vitamin D, and 19 more
1 easy-to-swallow capsule per day
Made in the US with globally sourced ingredients
Third-party lab tested

Learn More

Based on 3732 Reviews of Primal Harvest

CITATIONS

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Primal Harvest provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

Green R, Allen LH, Bjørke-Monsen AL, et al. Vitamin B12 deficiency [published correction appears in Nat Rev Dis Primers. 2017 Jul 20;3:17054]. Nat Rev Dis Primers. 2017;3:17040. Published 2017 Jun 29. doi:10.1038/nrdp.2017.40

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[1] This website is owned and operated by Primal Harvest® and BeautyLux® brands.

*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Note: The information contained within this site is not intended as a substitute for professional medical advice. If you have, expect to have, or suspect you may have any medical condition, you are urged to consult with a healthcare provider. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only. Results do not necessarily reflect typical results from the use of these products. Please visit product websites for more information.

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